The list is too large to save as a template. The size of a template cannot exceed 524288000 bytes.

Error:         The list is too large to save as a template. The size of a template cannot exceed 524288000 bytes. 

Limitation: There is Soft limit for List Template is 50 MB.
                 You can modify using below command :
                 stsadm -o setproperty -propertyname max-template-document-size -propertyvalue 50000000 
                 But this is hard limit to 500MB so we can't save list template more then 500MB size.

Resolution: You can move document using Explorer window but there is also one limitation (can't move metadata) 


Happy SharePointing...!!!

Microsoft SharePoint is not supported with version 4.0.30319.239 of the Microsoft .Net Runtime

SharePoint 2010 does not support access from .NET Framework 4 or being run in a .NET Framework 4 app domain.

Solution :
If you must support the .NET Framework 4, we recommend that you develop a web service that uses the .NET Framework 4 and then connect to it from SharePoint.

Limitation:
All server-side customizations directly for SharePoint 2010 still need to be either the .NET Framework 3.5 or the .NET Framework 3.5 SP1.

You can't directly give the reference of assembly which has run time framework is 4.0.


Happy SharePointing...!!!